Monodisperse cell-encapsulating peptide microgel beads for 3D cell culture.
作者： Yukiko Tsuda , Yuya Morimoto , Shoji Takeuchi
DOI: 10.1021/LA902827Y
关键词:
摘要: This paper describes a method to produce monodisperse cell-encapsulating microgel beads composed of self-assembling peptide gel for three-dimensional (3D) cell culture. We used 3D microfluidic axisymmetric flow-focusing device with an external gelation method. The finely powdered salts were dispersed into continuous phase, and the induced when in contact solution. Over 93% cells survived after encapsulation, migrated grew within gels. Applications our include bead-based assays drug testing engineering tissue constructs.
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