Identification of genetic variations of the human organic cation transporter hOCT1 and their functional consequences.
作者： Reinhold Kerb , Ulrich Brinkmann , Natalia Chatskaia , Dmitry Gorbunov , Valentin Gorboulev
DOI: 10.1097/00008571-200211000-00002
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摘要: By systematic mutation screening of the polyspecific organic cation transporter hOCT1 (SLC22A1) in 57 Caucasians, 25 genetic variations were identified and further analysed for population frequency. Five mutations resulting amino acid changes Arg61Cys, Cys88Arg, Phe160Leu, Gly401Ser, Met4
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