The pharmacogenetics of antidepressant treatments for depressive disorders
作者： Min-Soo Lee
DOI: 10.1002/DDR.20020
关键词:
摘要: Pharmacological treatments for depressive disorder vary between individuals, with 30–40% of patients not responding sufficiently to antidepressant drugs. Different genetic makeups are thought play an important role in the actions antidepressants, but there presently no gold-standard markers determining response antidepressants. In this report, we review work focused on association responses and polymorphisms, including serotonin transporter, tryptophan hydroxylase, receptor 2A, 6, G-protein β subunit, norepinephrine transporter. Drug Dev. Res. 65:170–178, 2005. © 2005 Wiley-Liss, Inc.
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