Palladium-catalyzed intramolecular C-arylation of benzylic carbon: synthesis of 3-benzoxazolylisoindolinones by a sequence of Ugi-4CR/postfunctionalization.
作者： Angela Salcedo , Luc Neuville , Jieping Zhu
DOI: 10.1021/JO800266Y
关键词:
摘要: Submitting Ugi-adduct 4 to two consecutive metal-catalyzed intramolecular reactions, namely copper-catalyzed O-arylation and palladium-catalyzed C-arylation of benzylic carbon developed in the course this study, affords benzoxazolylisoindolinones good excellent yields.
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