Methods, systems, and apparatuses for tissue ablation using pulse shape designs

作者: Liel Rubinsky , Boris Rubinsky , Michael Klaus Stehling , Paul Mikus , Enric Günther

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摘要: Example methods and apparatuses are disclosed for providing tissue ablation through electrolysis, electroporation, or a combination thereof. A way to deliver the pulse that has an element of gradual decay can thereby reduce both muscle contraction electric breakdown discharge at electrodes is disclosed. The apparatus may include electrode, power supply, controller. controller control charge applied electrode induce direct current treatment site produce electrolysis products voltage electroporation. duration magnitude determine dose degree permeabilization cells in site.

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