Huaier aqueous extract induces apoptosis of human fibrosarcoma HT1080 cells through the mitochondrial pathway

作者: YANG CUI , HONGMEI MENG , WEIDONG LIU , HUAN WANG , QINGPENG LIU

DOI: 10.3892/OL.2015.2906

关键词:

摘要: … the ability of Huaier extract to inhibit … that Huaier extract induced the apoptosis of HT1080 cells through the mitochondrial pathway. The results of the present study indicate that Huaier …

参考文章(21)
Seema Bagadey, Sharadini Dahanukar, Urmila Thatte, Modulation of programmed cell death by medicinal plants. Cellular and Molecular Biology. ,vol. 46, pp. 199- 214 ,(2000)
Shusen Zheng, Haiyang Xie, Xiao Xu, Qiang Wei, Kai Wang, Qi Ling, Lin Zhou, Anticancer effects of Huaier are associated with down-regulation of P53. Asian Pacific Journal of Cancer Prevention. ,vol. 12, pp. 2251- 2254 ,(2011)
Qiang Yu, Zhengqing Zhao, Jihu Sun, Wei Guo, Jiqiang Fu, Geoffrey Burnstock, Cheng He, Zhenghua Xiang, Expression of P2X 6 receptors in the enteric nervous system of the rat gastrointestinal tract Histochemistry and Cell Biology. ,vol. 133, pp. 177- 188 ,(2010) , 10.1007/S00418-009-0659-0
Jiasheng Zheng, Cong Li, Xia Wu, Mengmeng Liu, Xicai Sun, Yingzhuo Yang, Meijun Hao, Shoupeng Sheng, Yu Sun, Honghai Zhang, Jiang Long, Yi Liang, Caixia Hu, Huaier polysaccharides suppresses hepatocarcinoma MHCC97-H cell metastasis via inactivation of EMT and AEG-1 pathway. International Journal of Biological Macromolecules. ,vol. 64, pp. 106- 110 ,(2014) , 10.1016/J.IJBIOMAC.2013.11.034
Michael C Wei, Wei-Xing Zong, Emily H-Y Cheng, Tullia Lindsten, Vily Panoutsakopoulou, Andrea J Ross, Kevin A Roth, Grant R MacGregor, Craig B Thompson, Stanley J Korsmeyer, Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death Science. ,vol. 292, pp. 727- 730 ,(2001) , 10.1126/SCIENCE.1059108
Xiaohui Yan, Tianjiao Lyu, Nan Jia, Yinhua Yu, Keqin Hua, Weiwei Feng, Huaier aqueous extract inhibits ovarian cancer cell motility via the AKT/GSK3β/β-catenin pathway. PLOS ONE. ,vol. 8, ,(2013) , 10.1371/JOURNAL.PONE.0063731
JI HOON JANG, SEON MIN WOO, HEE JUNG UM, EUN JUNG PARK, KYOUNG-JIN MIN, TAE-JIN LEE, SANG HYUN KIM, YUNG HYUN CHOI, TAEG KYU KWON, RU486, a glucocorticoid receptor antagonist, induces apoptosis in U937 human lymphoma cells through reduction in mitochondrial membrane potential and activation of p38 MAPK Oncology Reports. ,vol. 30, pp. 506- 512 ,(2013) , 10.3892/OR.2013.2432
XIAOLONG WANG, NING ZHANG, QIANG HUO, MINGJUAN SUN, SHANGGE LV, QIFENG YANG, Huaier aqueous extract suppresses human breast cancer cell proliferation through inhibition of estrogen receptor α signaling International Journal of Oncology. ,vol. 43, pp. 321- 328 ,(2013) , 10.3892/IJO.2013.1947
G. Zhao, Y. Zhu, C. O. Eno, Y. Liu, L. DeLeeuw, J. A. Burlison, J. B. Chaires, J. O. Trent, C. Li, Activation of the Proapoptotic Bcl-2 Protein Bax by a Small Molecule Induces Tumor Cell Apoptosis Molecular and Cellular Biology. ,vol. 34, pp. 1198- 1207 ,(2014) , 10.1128/MCB.00996-13
Jianzhuang Ren, Chuansheng Zheng, Gansheng Feng, Huimin Liang, Xiangwen Xia, Jianlin Fang, Xuhua Duan, Hui Zhao, Inhibitory effect of extract of fungi of Huaier on hepatocellular carcinoma cells Journal of Huazhong University of Science and Technology [Medical Sciences]. ,vol. 29, pp. 198- 201 ,(2009) , 10.1007/S11596-009-0212-3