Cervicomedullary Injury After Pneumococcal Meningitis With Brain Edema

作者: RajaNandini Muralidharan , Alejandro A. Rabinstein , Eelco F. M. Wijdicks

DOI: 10.1001/ARCHNEUROL.2011.61

关键词:

摘要: Objectives To demonstrate a rare but potential mechanism of quadriplegia in patient with fulminant pneumococcal meningitis complicated by severe intracranial hypertension. Design Case report. Setting Intensive care unit. Patient A 21-year-old man who presented 3 days headache, combativeness, and fever. Intervention Antibiotics steroids were initiated after lumbar puncture yielded purulent cerebrospinal fluid streptococcus pneumoniae. Results The patient's course was cerebral edema necessitating pressure monitoring pressure–targeted therapy. Within 5 he developed areflexia. Brain cervical spine magnetic resonance imaging revealed patchy areas T2 signal hyperintensity associated gadolinium enhancement the superior spinal cord, cerebellar tonsils, medulla. Conclusions Quadriplegia secondary to tonsillar herniation is should be considered patients acute quadriparesis treatment increased pressure. Magnetic changes may demonstrated. Significant improvement cord symptoms can expected.

参考文章(19)
Margaret G. Norman, Respiratory arrest and cervical spinal cord infarction following lumbar puncture in meningitis. Canadian Journal of Neurological Sciences. ,vol. 9, pp. 443- 447 ,(1982) , 10.1017/S0317167100044371
A. Di Rienzo, M. Iacoangeli, F. Rychlicki, S. Veccia, M. Scerrati, Decompressive craniectomy for medically refractory intracranial hypertension due to meningoencephalitis: report of three patients. Acta Neurochirurgica. ,vol. 150, pp. 1057- 1065 ,(2008) , 10.1007/S00701-008-0019-1
Stefan Kastenbauer, Frank Winkler, Gunther Fesl, Xaver Schiel, Helmut Ostermann, Tarek A. Yousry, Hans Walter Pfister, Acute severe spinal cord dysfunction in bacterial meningitis in adults: MRI findings suggest extensive myelitis. JAMA Neurology. ,vol. 58, pp. 806- 810 ,(2001) , 10.1001/ARCHNEUR.58.5.806
Diederik van de Beek, Jan de Gans, Allan R. Tunkel, Eelco F.M. Wijdicks, Community-Acquired Bacterial Meningitis in Adults New England Journal of Medicine. ,vol. 354, pp. 44- 53 ,(2006) , 10.1056/NEJMRA052116
Juan M. Flores-Cordero, Rosario Amaya-Villar, Maria D. Rinc�n-Ferrari, Santiago R. Leal-Noval, Jos� Garnacho-Montero, Ana C. Llanos-Rodr�guez, Francisco Murillo-Cabezas, Acute community-acquired bacterial meningitis in adults admitted to the intensive care unit: clinical manifestations, management and prognostic factors. Intensive Care Medicine. ,vol. 29, pp. 1967- 1973 ,(2003) , 10.1007/S00134-003-1935-4
G Rennick, F Shann, J de Campo, Cerebral herniation during bacterial meningitis in children. BMJ. ,vol. 306, pp. 953- 955 ,(1993) , 10.1136/BMJ.306.6883.953
Diederik van de Beek, Martijn Weisfelt, Jan de Gans, Allan R Tunkel, Eelco FM Wijdicks, Drug insight: adjunctive therapies in adults with bacterial meningitis Nature Reviews Neurology. ,vol. 2, pp. 504- 516 ,(2006) , 10.1038/NCPNEURO0265
M. Weisfelt, D. Beek, J. Gans, Dexamethasone treatment in adults with pneumococcal meningitis: risk factors for death. European Journal of Clinical Microbiology & Infectious Diseases. ,vol. 25, pp. 73- 78 ,(2006) , 10.1007/S10096-006-0089-Z
P-O. Grände, E. B. Myhre, C-H. Nordström, S. Schliamser, Treatment of intracranial hypertension and aspects on lumbar dural puncture in severe bacterial meningitis. Acta Anaesthesiologica Scandinavica. ,vol. 46, pp. 264- 270 ,(2002) , 10.1034/J.1399-6576.2002.460307.X