Outwitting Evolution: Fighting Drug-Resistant TB, Malaria, and HIV
作者： Daniel E. Goldberg , Robert F. Siliciano , William R. Jacobs
DOI: 10.1016/J.CELL.2012.02.021
关键词:
摘要: Although caused by vastly different pathogens, the world's three most serious infectious diseases, tuberculosis, malaria, and HIV-1 infection, share common problem of drug resistance. The pace development has been very slow for tuberculosis malaria rapid HIV-1. But each disease, resistance to drugs appeared quickly after introduction drug. Learning how manage prevent is a major medical challenge that requires an understanding evolutionary dynamics pathogen. This Review summarizes similarities differences in evolution these pathogens.
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