A discrete choice experiment to determine patient preferences for injection devices in multiple sclerosis
作者： S. L. Shingler , P. Swinburn , S. Ali , R. Perard , A. J. Lloyd
DOI: 10.3111/13696998.2013.811079
关键词:
摘要: AbstractObjective:Relapsing-remitting multiple sclerosis (MS) is usually managed with disease modifying drugs (DMDs), most commonly administered via self-injection. The aim of this study was to estimate the influence that different treatment-related attributes have for MS patients on their choice DMD device. By establishing relative importance these characteristics it should be possible better understand acceptability a given device and optimize development future devices.Methods:A discrete experiment (DCE) survey developed basis review published literature. Attributes identified inclusion in were: ease use; comfort presence additional functions, needle visibility; practicality efficacy. Choice sets were presented as pairs hypothetical treatments based upon fractional factorial design. One-hundred device-using completed online. Analysis conducted using mixed-logit appr...
informahealthcare.com参考文章(18)
David A. Hensher, Joffre D. Swait, Jordan J. Louviere, Stated Choice Methods: Analysis and Applications ,(2000)
V. Devonshire, Y. Lapierre, R. Macdonell, C. Ramo-Tello, F. Patti, P. Fontoura, L. Suchet, R. Hyde, I. Balla, E. M. Frohman, B. C. Kieseier, , The Global Adherence Project (GAP): a multicenter observational study on adherence to disease‐modifying therapies in patients with relapsing‐remitting multiple sclerosis European Journal of Neurology. ,vol. 18, pp. 69- 77 ,(2011) , 10.1111/J.1468-1331.2010.03110.X
Hervé Dumas, Paris Panayiotopoulos, Dorothy Parker, Vincent Pongpairochana, Understanding and meeting the needs of those using growth hormone injection devices. BMC Endocrine Disorders. ,vol. 6, pp. 5- 5 ,(2006) , 10.1186/1472-6823-6-5
M. Ryan, Using conjoint analysis to elicit preferences for health care BMJ. ,vol. 320, pp. 1530- 1533 ,(2000) , 10.1136/BMJ.320.7248.1530
Verdun di Cantogno, Russell, Tom Snow, Understanding and meeting injection device needs in multiple sclerosis: a survey of patient attitudes and practices. Patient Preference and Adherence. ,vol. 5, pp. 173- 180 ,(2011) , 10.2147/PPA.S14903
Howard Zwibel, Gabriel Pardo, Shelly Smith, Douglas Denney, MerriKay Oleen-Burkey, A multicenter study of the predictors of adherence to self-injected glatiramer acetate for treatment of relapsing-remitting multiple sclerosis Journal of Neurology. ,vol. 258, pp. 402- 411 ,(2011) , 10.1007/S00415-010-5766-2
M. J. Hohol, E. J. Orav, H. L. Weiner, Disease steps in multiple sclerosis: a simple approach to evaluate disease progression. Neurology. ,vol. 45, pp. 251- 255 ,(1995) , 10.1212/WNL.45.2.251
Nina Grytten, Per Måseide, 'When I am together with them I feel more ill.' The stigma of multiple sclerosis experienced in social relationships. Chronic Illness. ,vol. 2, pp. 195- 208 ,(2006) , 10.1177/17423953060020030101
Mandy Ryan, Discrete choice experiments in health care BMJ. ,vol. 328, pp. 360- 361 ,(2004) , 10.1136/BMJ.328.7436.360
J. A. Cramer, B. J. Cuffel, V. Divan, A. Al-Sabbagh, M. Glassman, Patient satisfaction with an injection device for multiple sclerosis treatment. Acta Neurologica Scandinavica. ,vol. 113, pp. 156- 162 ,(2006) , 10.1111/J.1600-0404.2005.00568.X