Configuration and conformation of the A-ring of 1-methyl steroids
作者： W.J. Wechter , G. Slomp , F.A. MacKellar , R. Wiechert , U. Kerb
DOI: 10.1016/S0040-4020(01)98325-5
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摘要: Abstract A detailed NMR analysis of epimeric pairs 1-methylated steroids in the A/B cis and Δ4-series has confirmed earlier configurational assignments. One-methyl trans series 1-methyl hydrocortisone synthesized therefrom are revised from α to β-configuration. One-β-methyl-5α 1β-methyl-Δ4 were judged be distorted normal chair-formed A-ring conformation, former into twist latter alternative half-chair form.
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