Predictors of mortality in surgical patients with Acinetobacter baumannii bacteremia.

作者: Su-Jung Chen , Tze-Fan Chao , Mei-Chun Chiang , Shu-Chen Kuo , Liang-Yu Chen

DOI: 10.1016/J.JMII.2011.01.017

关键词:

摘要: Background Acinetobacter baumannii has emerged as an important pathogen of nosocomial infection. The aim this study was to evaluate the predictors poor outcome in surgical patients with A bacteremia. Methods We retrospectively recruited a total 50 who developed bacteremia within 2 weeks after surgery during 113-month period. primary for all-cause 14-day mortality. Clinical and laboratory data, antimicrobial susceptibility, treatment, Sequential Organ Failure Assessment (SOFA) score were evaluated possible outcome. Results mortality 20% there no association between type SOFA only independent predictor adjustment other variables. calibration acceptable (Hosmer-Lemeshow χ  = 3.65, p  = 0.72) discrimination good (area under receiver operating characteristic curve: 0.80 ± 0.07, 95% confidence interval, 0.67–0.94). found that ≥7 significant Conclusions assessed at onset is reliable tool predicting

参考文章(28)
C E Liu, W W Wong, C P Fung, S Y Lin, C Y Liu, Acinetobacter calcoaceticus-baumannii complex bacteremia: analysis of 82 cases. Journal of Microbiology Immunology and Infection. ,vol. 31, pp. 119- 124 ,(1998)
Wing Wai Wong, Chang Phone Fung, Cheng Yi Liu, Kwok Woon Yu, Chung Hsu Lai, Hsin Pai Chen, Te Li Chen, Predictors of mortality in Acinetobacter baumannii bacteremia. Journal of Microbiology Immunology and Infection. ,vol. 38, pp. 127- 136 ,(2005)
J.M. Cisneros, J. Rodríguez-Baño, Nosocomial bacteremia due to Acinetobacter baumannii: epidemiology, clinical features and treatment Clinical Microbiology and Infection. ,vol. 8, pp. 687- 693 ,(2002) , 10.1046/J.1469-0691.2002.00487.X
J. -L. Vincent, R. Moreno, J. Takala, S. Willatts, A. De Mendonça, H. Bruining, C. K. Reinhart, P. M. Suter, L. G. Thijs, The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine. Intensive Care Medicine. ,vol. 22, pp. 707- 710 ,(1996) , 10.1007/BF01709751
L-Y Huang, T-L Chen, P-L Lu, C-A Tsai, W-L Cho, F-Y Chang, C-P Fung, LK Siu, None, Dissemination of multidrug-resistant, class 1 integron-carrying Acinetobacter baumannii isolates in Taiwan Clinical Microbiology and Infection. ,vol. 14, pp. 1010- 1019 ,(2008) , 10.1111/J.1469-0691.2008.02077.X
Anna S Levin, Carlos E Levy, A Edison I Manrique, Eduardo AS Medeiros, Silvia F Costa, None, Severe nosocomial infections with imipenem-resistant Acinetobacter baumannii treated with ampicillin/sulbactam. International Journal of Antimicrobial Agents. ,vol. 21, pp. 58- 62 ,(2003) , 10.1016/S0924-8579(02)00276-5
J. M. Cisneros, M. J. Reyes, J. Pachon, B. Becerril, F. J. Caballero, J. L. Garcia Garmendia, C. Ortiz, A. R. Cobacho, Bacteremia Due to Acinetobacter baumannii: Epidemiology, Clinical Findings, and Prognostic Features Clinical Infectious Diseases. ,vol. 22, pp. 1026- 1032 ,(1996) , 10.1093/CLINIDS/22.6.1026
Flavio Lopes Ferreira, Daliana Peres Bota, Annette Bross, Christian Mélot, Jean-Louis Vincent, Serial Evaluation of the SOFA Score to Predict Outcome in Critically Ill Patients JAMA. ,vol. 286, pp. 1754- 1758 ,(2001) , 10.1001/JAMA.286.14.1754
Jean-Louis Vincent, Arnaldo de Mendonca, Francis Cantraine, Rui Moreno, Jukka Takala, Peter M. Suter, Charles L. Sprung, Francis Colardyn, Serge Blecher, Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: Results of a multicenter, prospective study Critical Care Medicine. ,vol. 26, pp. 1793- 1800 ,(1998) , 10.1097/00003246-199811000-00016