ParkDB: a Parkinson’s disease gene expression database
作者： C. Taccioli , V. Maselli , J. Tegner , D. Gomez-Cabrero , G. Altobelli
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摘要: Parkinson's disease (PD) is a common, adult-onset, neuro-degenerative disorder characterized by the degeneration of cardinal motor signs mainly due to loss dopaminergic neurons in substantia nigra. To date, researchers still have limited understanding key molecular events that provoke neurodegeneration this disease. Here, we present ParkDB, first queryable database dedicated gene expression PD. ParkDB contains complete set re-analyzed, curated and annotated microarray datasets. This resource enables scientists identify compare signatures involved PD neuron differentiation under different biological conditions across species. Database URL: http://www2.cancer.ucl.ac.uk/Parkinson_Db2/
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