Application of Transgenes and Transgenic Mice to Study Gene Activity from the Oocyte to the Early Embryo

摘要: Development is initiated during gametogenesis. The contribution of the oocyte has been precisely defined in a few species, such as invertebrates, using genetic approaches (St Johnston and Nusslein-Volhard 1992), also certain vertebrates, amphibians, biochemical analyzes (Ruiz i Altaba Melton 1990; Kessler 1994). However, steps embryogenesis that occur prior to gastrulation exhibit surprisingly large diversity among different zoologic groups. It therefore impossible extrapolate rules or strategies and, so far, no conserved developmental pathways have found.