FOXC1 plays a crucial role in the growth of pancreatic cancer.
作者： Ramadevi Subramani , Fernando A. Camacho , Carly Ivy Levin , Kristina Flores , Alexa Clift
DOI: 10.1038/S41389-018-0061-7
关键词:
摘要: … on crucial transcription factors and identified the FOXC1 as one of the crucial regulator of IGF-… silence FOXC1 in pancreatic cancer cells. Our results demonstrate that IGF-1R and FOXC1 …
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sci-hub.se 参考文章(34)
Jacqueline Banyard, Diane R. Bielenberg, The role of EMT and MET in cancer dissemination Connective Tissue Research. ,vol. 56, pp. 403- 413 ,(2015) , 10.3109/03008207.2015.1060970
Hyo Jung Kim, Chae Lim Jung, Yeon Shin Jeong, Jong-Sang Kim, Soybean-derived glyceollins induce apoptosis through ROS generation. Food & Function. ,vol. 5, pp. 688- 695 ,(2014) , 10.1039/C3FO60379B
J Wang, P S Ray, M-S Sim, X Z Zhou, K P Lu, A V Lee, X Lin, S P Bagaria, A E Giuliano, X Cui, FOXC1 regulates the functions of human basal-like breast cancer cells by activating NF-κB signaling. Oncogene. ,vol. 31, pp. 4798- 4802 ,(2012) , 10.1038/ONC.2011.635
Limin Xia, Wenjie Huang, Dean Tian, Hongwu Zhu, Xingshun Qi, Zheng Chen, Yongguo Zhang, Hao Hu, Daiming Fan, Yongzhan Nie, Kaichun Wu, Overexpression of forkhead box C1 promotes tumor metastasis and indicates poor prognosis in hepatocellular carcinoma Hepatology. ,vol. 57, pp. 610- 624 ,(2013) , 10.1002/HEP.26029
Steven T. Sizemore, Ruth A. Keri, The Forkhead Box Transcription Factor FOXC1 Promotes Breast Cancer Invasion by Inducing Matrix Metalloprotease 7 (MMP7) Expression Journal of Biological Chemistry. ,vol. 287, pp. 24631- 24640 ,(2012) , 10.1074/JBC.M112.375865
Ramadevi Subramani, Rebecca Lopez-Valdez, Arunkumar Arumugam, Sushmita Nandy, Thiyagarajan Boopalan, Rajkumar Lakshmanaswamy, Targeting Insulin-Like Growth Factor 1 Receptor Inhibits Pancreatic Cancer Growth and Metastasis PLoS ONE. ,vol. 9, pp. e97016- ,(2014) , 10.1371/JOURNAL.PONE.0097016
Jennifer E. Yeh, Patricia A. Toniolo, David A. Frank, Targeting transcription factors: promising new strategies for cancer therapy. Current Opinion in Oncology. ,vol. 25, pp. 652- 658 ,(2013) , 10.1097/01.CCO.0000432528.88101.1A
David T. Denhardt, Oncogene-initiated aberrant signaling engenders the metastatic phenotype: synergistic transcription factor interactions are targets for cancer therapy. Critical Reviews in Oncogenesis. ,vol. 7, pp. 261- 291 ,(1996) , 10.1615/CRITREVONCOG.V7.I3-4.70
Jeffrey A. Toretsky, Thea Kalebic, Vicki Blakesley, Derek LeRoith, Lee J. Helman, The Insulin-like Growth Factor-I Receptor Is Required for EWS/FLI-1 Transformation of Fibroblasts Journal of Biological Chemistry. ,vol. 272, pp. 30822- 30827 ,(1997) , 10.1074/JBC.272.49.30822
A. H. Brivanlou, Signal Transduction and the Control of Gene Expression Science. ,vol. 295, pp. 813- 818 ,(2002) , 10.1126/SCIENCE.1066355