Functional connections between the pineal gland and immune system.

摘要: Experimental findings which support a functional connection between the pineal gland and immune system in mammals birds are summarized. Developmental age-related changes function appear, at least partially, to be related with efficiency. Mechanisms whereby melatonin influences complex, but include participation of mediators (endogenous opioids, cytokines, hormones, zinc pool) as well specific binding sites on cells. Melatonin, highly lyophilic compound, may also penetrate cells without mediation receptors act within potent free radical scavenger an anti-aging oncostatic factor. The may, turn, via synthesis secretion soluble factors, influence function, thereby closing information loop maintain homeostasis order face harmful environment.