Pharmaceutical Compound Crystallization: Growth Mechanism of Needle‐Like Crystals
作者： P. Taulelle , J. P. Astier , C. Hoff , G. Pèpe , S. Veesler
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摘要: In this paper, crystallization of needle-like crystals is investigated using both experimental and numerical approaches. The structure, morphology, habit, growth behavior Irbesatan phase A grown from 2-propanol solution are studied. case, molecular modeling shows an unusually high anisotropy the internal crystal leading to prediction acicular habit which in good agreement with habit. Irbesartan example for properties governed by rather than external properties. influence conditions situ ex monitoring, namely optical microscopy AFM. These investigations show that agglomerated same crystallographic orientation as individual constituent; was explained regular over-and intergrowths case twinning.
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