Release of preventive agents from pacifiers in vitro. An introduction to a novel preventive measure.

摘要: Clinical data show that the later primary teeth are colonized by mutans streptococci (MS), less caries will develop, if at all. Since up to 90% of teething children develop a sucking habit, pacifiers were designed release preventive agents into mouth. Simultaneous use sodium fluoride and xylitol increases enamel content. Xylitol affects specifically growth metabolism streptococci. The aim this study was determine fluoride, sorbitol from in vitro. A disintegration apparatus test dissolution tablets containing NaF resp. 0.25 mg F, 160 150 pacifiers. Six agitated simultaneously with standardised pump movement, 30 strokes/min, 15 ml normal saline +37 degrees C for 2, 5, 10, 20, 40, 60 90 min. released determined 1 samples which Tisab added using combined F-ion electrode. analyzed an ion chromatograph pulsed-amperometric detector. linear slow could be observed After 2700 strokes residual suction chambers (vol. approximately 0.4 ml) equally analyzed, where all 3 ingredients still detected.