Efficacy of a slow-release device containing fluoride, xylitol and sorbitol in preventing infant caries

摘要: A novel slow-release administration device, the ''Fall-Asleep Pacifier'' (FAP), was studied as a prophylactic measure against mutans streptococcal oral infection and dental caries in risk group of 1-year-old children by comparing test (T, n = 34) control (C, 88) groups prospective cohort study. In T received their fluoride tablets (Fludent®, containing NaF corresp. 0.25 mg F-, xylitol 159 sorbitol 153 mg) evenings FAP. C same dose Fludent® crushed food evenings. The proportion children, whose plaque samples from upper incisors were streptococcus positive at age 24 months, significantly (P < 0.05) greater (25%) than (9%). developed 0.001) less (none) new dentinal carious lesions primary dentitions between 2 3½ years age. Fifty-four percent chil...