Basal forebrain cholinergic lesions in 7-day-old rats alter ultrasound vocalisations and homing behaviour.

作者: Maria Luisa Scattoni , Maria Puopolo , Gemma Calamandrei , Laura Ricceri

DOI: 10.1016/J.BBR.2005.01.011

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摘要: We analysed the effects of 192 IgG-saporin lesions on pnd 7 upon neonatal behavioural responses. Number ultrasonic vocalisations (USVs) were recorded pnds 9, 11 and 13. On 13 rats underwent a homing test to measure olfactory orientation towards nest material. reduced number USVs at all ages considered while increasing entrancies into area. These data suggest that early damage basal forebrain cholinergic nuclei induces significant changes in rat repertoire as second-postnatal week.

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