ACCELERATING THE DIAGNOSIS OF AMYOTROPHIC LATERAL SCLEROSIS

摘要: BACKGROUND- Amyotrophic lateral sclerosis (ALS) is the most common form of motor neuron disease in adults and a relatively frequent cause progressive weakness. Early recognition ALS may be difficult because its insidious onset variable distribution clinical involvement at presentation. In past, inexorable progression lack effective drugs did not favor prompt diagnosis. The recent approval first drug for ALS, riluzole, wider availability centers with experience care patients has made an accelerated diagnosis beneficial to patient. REVIEW SUMMARY- this article, I review process diagnosing efficient manner, focusing on use set electrodiagnostic criteria including algorithm as aid making timely accuracy diagnostic criteria, well false-positive false-negative diagnoses, reviewed. To recognizing early course, presentations that mistaken other disorders are discussed. article concludes discussion laboratory tests. CONCLUSIONS- sufficiently should considered differential focal, atrophic weakness without sensory disturbance adult any age.