Antibody responses to the merozoite surface protein-1 complex in cerebral malaria patients in India.
作者： Naomi W Lucchi , Jon Eric Tongren , Vidhan Jain , Avinash C Nagpal , Christian W Kauth
关键词:
摘要: Background Plasmodium falciparum infection causes cerebral malaria (CM) in a subset of patients with anti-malarial treatment protecting only about 70% to 80% patients. Why develops CM complications, including neurological sequelae or death, is still not well understood. It believed that host immune factors may modulate outcomes and there substantial evidence cellular factors, such as cytokines, play an important role this process. In study, the potential relationship between antibody responses merozoite surface protein (MSP)-1 complex (which consists four fragments namely: MSP-183, MSP-130, MSP-138 MSP-142), MSP-636 MSP-722 was investigated.
biomedcentral.com
springer.com
cdc.gov
doaj.org参考文章(64)
V P Sharma, Re-emergence of malaria in India. Indian Journal of Medical Research. ,vol. 103, pp. 26- 45 ,(1996)
N Singh, N Valecha, None, Evaluation of a rapid diagnostic test, 'Determine malaria pf', in epidemic-prone, forest villages of central India (Madhya Pradesh). Annals of Tropical Medicine and Parasitology. ,vol. 94, pp. 421- 427 ,(2000) , 10.1080/00034983.2000.11813560
H Giha, L Hviid, I M Elhassan, C Roper, J S McBride, A A Holder, D R Cavanagh, V J Robinson, D E Arnot, T G Theander, A Longitudinal Study of Type-Specific Antibody Responses to Plasmodium falciparum Merozoite Surface Protein-1 in an Area of Unstable Malaria in Sudan Journal of Immunology. ,vol. 161, pp. 347- 359 ,(1998)
D. C. Kaslow, Venkatachalam Udhayakumar, W. Weiss, Ya Ping Shi, S. Kariuki, A. A. Lal, O. H. Branch, D. Anyona, B. L. Nahlen, P. B. Bloland, Identification of T and B cell epitopes recognized by humans in the C-terminal 42-kDa domain of the Plasmodium falciparum merozoite surface protein (MSP)-1. Journal of Immunology. ,vol. 154, pp. 6022- 6030 ,(1995)
O H Branch, A J Oloo, A A Lal, P B Bloland, W A Hawley, V Udhayakumar, A W Hightower, D C Kaslow, B L Nahlen, A longitudinal investigation of IgG and IgM antibody responses to the merozoite surface protein-1 19-kiloDalton domain of Plasmodium falciparum in pregnant women and infants: associations with febrile illness, parasitemia, and anemia. American Journal of Tropical Medicine and Hygiene. ,vol. 58, pp. 211- 219 ,(1998) , 10.4269/AJTMH.1998.58.211
Y P Shi, U Sayed, S H Qari, J M Roberts, V Udhayakumar, A J Oloo, W A Hawley, D C Kaslow, B L Nahlen, A A Lal, Natural immune response to the C-terminal 19-kilodalton domain of Plasmodium falciparum merozoite surface protein 1. Infection and immunity. ,vol. 64, pp. 2716- 2723 ,(1996) , 10.1128/IAI.64.7.2716-2723.1996
Clinical Features and Prognostic Indicators in Paediatric Cerebral Malaria: A Study of 131 Comatose Malawian Children QJM: An International Journal of Medicine. ,vol. 71, pp. 441- 459 ,(1989) , 10.1093/OXFORDJOURNALS.QJMED.A068338
B. Y. Sarfo, S. Singh, J. W. Lillard, A. Quarshie, R. K. Gyasi, H. Armah, A. A. Adjei, P. Jolly, J. K. Stiles, The cerebral-malaria-associated expression of RANTES, CCR3 and CCR5 in post-mortem tissue samples Annals of Tropical Medicine and Parasitology. ,vol. 98, pp. 297- 303 ,(2004) , 10.1179/000349804225003271
Carlotta Trucco, Delmiro Fernandez-Reyes, Steven Howell, William H. Stafford, Terry J. Scott-Finnigan, Munira Grainger, Solabomi A. Ogun, William R. Taylor, Anthony A. Holder, The merozoite surface protein 6 gene codes for a 36 kDa protein associated with the Plasmodium falciparum merozoite surface protein-1 complex. Molecular and Biochemical Parasitology. ,vol. 112, pp. 91- 101 ,(2001) , 10.1016/S0166-6851(00)00350-9
ANDREA F. EGAN, PETRA BURGHAUS, PIERRE DRUILHE, ANTHONY A. HOLDER, ELEANOR M. RILEY, Human antibodies to the 19 kDa C‐terminal fragment of Plasmodium falciparum merozoite surface protein 1 inhibit parasite growth in vitro Parasite Immunology. ,vol. 21, pp. 133- 139 ,(1999) , 10.1046/J.1365-3024.1999.00209.X