Four-component, five-centered, one-pot synthesis of 1-(1H-tetrazol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole derivatives
作者： B.V. Subba Reddy , Kavya Kota , B. Maheshwar Rao , B. Sridhar , K. Mukkanti
DOI: 10.1016/J.TETLET.2016.08.067
关键词:
摘要: Abstract An efficient four component, five centered coupling strategy has been developed for the synthesis of a novel series 1-tetrazolyl-tetrahydro-β-carboline derivatives in good yields. This method is effective tetrazolyl tetrahydro-β-carbolines one-pot operation. operationally simple and works under mild conditions with diverse substrates.
sci-hub.se 参考文章(39)
Rachel Scheffelaar, Eelco Ruijter, Romano V. A. Orru, Multicomponent Reaction Design Strategies: Towards Scaffold and Stereochemical Diversity Synthesis of Heterocycles via Multicomponent Reactions II. ,vol. 25, pp. 95- 126 ,(2010) , 10.1007/7081_2010_44
Ran Wu, Shang Gao, Xu Chen, Guanghui Yang, Lingling Pan, Gaobo Hu, Ping Jia, Weihui Zhong, Chuanming Yu, Synthesis of 1‐(1H‐Tetrazol‐5‐yl)‐2H‐isoindole Derivatives through Ugi Four‐Component and Silver‐Catalyzed Reactions European Journal of Organic Chemistry. ,vol. 2014, pp. 3379- 3386 ,(2014) , 10.1002/EJOC.201402098
B.V. Subba Reddy, A. Venkata Ganesh, M. Vani, T. Ramalinga Murthy, Shasi V Kalivendi, J.S. Yadav, Thee-component, one-pot synthesis of hexahydroazepino[3,4-b]indole and tetrahydro-1H-pyrido[3,4-b]indole derivatives and evaluation of their cytotoxicity. Bioorganic & Medicinal Chemistry Letters. ,vol. 24, pp. 4501- 4503 ,(2014) , 10.1016/J.BMCL.2014.07.084
Vommina V. Sureshbabu, Rao Venkataramanarao, Shankar A. Naik, G. Chennakrishnareddy, Synthesis of tetrazole analogues of amino acids using Fmoc chemistry: isolation of amino free tetrazoles and their incorporation into peptides Tetrahedron Letters. ,vol. 48, pp. 7038- 7041 ,(2007) , 10.1016/J.TETLET.2007.07.129
Carlos F. Marcos, Stefano Marcaccini, Gloria Menchi, Roberto Pepino, Tomás Torroba, Studies on isocyanides: synthesis of tetrazolyl-isoindolinones via tandem Ugi four-component condensation/intramolecular amidation Tetrahedron Letters. ,vol. 49, pp. 149- 152 ,(2008) , 10.1016/J.TETLET.2007.10.154
José Luis García Ruano, José Alemán, M. Belén Cid, Quick access to optically pure 2-(1-hydroxybenzyl)piperidine and pyrrolidine Synthesis. ,vol. 2006, pp. 687- 691 ,(2006) , 10.1055/S-2006-926306
Aino Laine, Christopher Lood, Ari Koskinen, Pharmacological Importance of Optically Active Tetrahydro-β-carbolines and Synthetic Approaches to Create the C1 Stereocenter Molecules. ,vol. 19, pp. 1544- 1567 ,(2014) , 10.3390/MOLECULES19021544
Gijs Koopmanschap, Eelco Ruijter, Romano VA Orru, Isocyanide-based multicomponent reactions towards cyclic constrained peptidomimetics Beilstein Journal of Organic Chemistry. ,vol. 10, pp. 544- 598 ,(2014) , 10.3762/BJOC.10.50
M. H. V. Huynh, M. D. Coburn, T. J. Meyer, M. Wetzler, Green primary explosives: 5-nitrotetrazolato-N2-ferrate hierarchies. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 103, pp. 10322- 10327 ,(2006) , 10.1073/PNAS.0604241103
Cheng-Xi Wei, Ming Bian, Guo-Hua Gong, Tetrazolium compounds: synthesis and applications in medicine. Molecules. ,vol. 20, pp. 5528- 5553 ,(2015) , 10.3390/MOLECULES20045528