PRKAA1 rs13361707 C/T polymorphism confers decreased susceptibility to esophageal cancer: A case-control study.

作者: Cheng‐Lin Li , Jian‐Qiang Zhao , Bao Zang

DOI: 10.1002/JCLA.23406

关键词:

摘要: Background Several studies probed into the connection between esophageal cancer (EC) risk and PRKAA1 rs13361707 C/T polymorphism, but obtained insignificant findings. Methods In this study, 814 EC cases 961 controls from Eastern China were recruited to validate relationship polymorphism susceptibility. Results Data suggested in gene was significantly related with a lower for EC. Such significant also uncovered subgroups of males, smokers, drinkers individuals age ≥ 60 years. addition, linked pathological grading, distant metastasis, histology Conclusion summary, is clinical properties patients East China.

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