[Patients with oral anticoagulation--bridging anticoagulation in the perioperative phase].

摘要: Oral anticoagulation with a vitamin K-antagonist requires special consideration when surgery or interventional procedures are planned. This is mainly due to the half life of K-antagonists and need for safe effective prior during as well in postoperative period. So far, continuous infusion unfractionated heparin (UFH) has been medication choice "bridge" patients surgery. The use low molecular weight heparins (LMWH) prospectively investigated this setting represents alternative. advantages LMWH better dose-response relationship reduced monitoring. facilitates bridging procedure be started out hospital, which may reduce hospital stay associated costs. Furthermore, so-called oral reduces bleeding complications maintains at risk.