Comparison of multianalyte immunosensor formats for on-line determination of organic compounds.

摘要: Studies leading to the development of multianalyte immunosensing approaches are presented herein. Competitive capture formats developed for carbaryl, atrazine, and irgarol 1051 as target compounds. Three proposals have been tested:  sequential, additive, simultaneous formats. For individual determinations, best format is sequential mode; additive mode useful only qualitative analyses; preferable screening purposes. The proposed systems show be advantageous over single-analyte sensors other approaches. In all cases, sensitivity reached (limit detection) high enough analysis samples containing levels each pesticide lower than 0.1 μg/L, sensor reusability very good (>600 determinations). applicability immunosensors on-line pollution surveillance in natural waters, well their advantages limitations, discussed.