Somatostatin and insulin secretion.
作者： Suad Efendic , Per-Eric Lins , Rolf Luft
DOI: 10.1016/0026-0495(78)90058-6
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摘要: Abstract The inhibitory effect of somatostatin was first demonstrated in vitro studies rat pituitary cell cultures. Thus, initially, its action on the release hormones man and animals main focus interest. While investigating growth hormone we, as well other groups, made unexpected observation that peptide also inhibited insulin release. 1–5 appeared to be second physiological compound with a direct release, catecholamines being first. This great interest us, since, for considerable period time, we had been spokesmen idea impaired is primary derangement all stages diabetes mellitus. Therefore, detailed study endocrine pancreas rats man.
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