作者: John H. Overton
DOI: 10.1177/074823379000600513
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摘要: The development of a physiologically based pharmacokinetic model for the whole body in which inhalation, exhalation, and metabolism respiratory tract tissues are taken into account is described. As an example model's use, results several experiments rats humans were exposed to styrene simulated; these discussed. predicted agree with empirical data modeling others.