作者: Christiane Bode , J Christian Bode
DOI: 10.1016/S1521-6918(03)00034-9
关键词:
摘要: Consumption of large quantities alcoholic beverages leads to disturbances in the intestinal absorption nutrients including several vitamins. The inhibition sodium and water caused by alcohol contributes tendency alcoholics develop diarrhoea. Excessive consumption (even a single episode) can result duodenal erosions bleeding mucosal injury upper jejunum. An increased prevalence for bacterial overgrowth small intestine may contribute functional and/or morphological abnormalities this part gut also non-specific abdominal complaints alcoholics. damage increases permeability macromolecules. This facilitates translocation endotoxin other toxins from lumen portal blood, thereby increasing liver's exposure these and, consequently, risk liver injury. results recent experimental studies support assumption that significantly modulates immune system gut.