Zollinger–Ellison Syndrome

摘要: The discovery of omeprazole and the subsequent development other proton pump inhibitors (lansoprazole, pantoprazole) has had a profound effect on management Zollinger-Ellison syndrome (ZES) as well gastric hypersecretory states.These drugs have now become choice for these conditions [1]. focus this chapter will be their impact syndrome, because all states disease demonstrates most acid hypersecretion been best studied. Although there are few studies with lansoprazole pantoprazole (Tab. 1), detailed 1) [2–13] performed using omeprazole, so primarily emphasized in chapter. To understand treatment ZES, it is essential to regimens that existed prior its introduction early 1980s ZES [2, 3, 14].