Omeprazole: Effective, Convenient Therapy for Zollinger—Ellison Syndrome

作者: Katherine E. Mcarthur , Martin J. Collen , Paul N. Maron , Jay A. Cherner , John M. Howard

DOI: 10.1016/S0016-5085(85)80011-1

关键词:

摘要: The acute and long-term effects of omeprazole on gastric acid secretion were examined in 11 patients with Zollinger-Ellison syndrome. Basal was inhibited by 50% 3 h after a single 60mg dose 78% 4 administration omeprazole. Patients treated daily omeprazole, the requirement defined as lowest that would reduce to 48 Omeprazole continued inhibit during 1–9 mo therapy remained free toxicity or side related is highly effective inhibitor Because its potency long duration action, offers an advance convenient medical for syndrome compared histamine H 2 -receptor antagonists.

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