Reliability of Symptoms in Assessing Control of Gastric Acid Secretion in Patients With Zollinger-Ellison Syndrome

作者: J-P. Raufman , S.M. Collins , S.J. Pandol , L.Y. Korman , M.J. Collen

DOI: 10.1016/S0016-5085(83)80173-5

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摘要: In the present study we explored whether presence or absence of symptoms could provide a reliable way assessing adequacy control gastric secretion in patients with Zollinger-Ellison syndrome who were treated medically. Over 5-yr period, 26 entered into prospective which examined that are associated hypersecretion, upper gastrointestinal pathology, and degree acid secretion. During their last admission, 15 (58%) symptomatic, but post-drug for 2 h before next dose medication was not significantly different from asymptomatic patients. This lack correlation between evident group as whole, well 8 12 underwent multiple admissions. Of 23 endoscopy x-rays, both, on had pathology. Post-drug less without pathology than those Furthermore, whom ≤ 10 mEq/h, criterion acceptable used this study, did occur. These findings demonstrate cannot be to assess medical syndrome. our opinion, maintenance mEq/h is an long-term

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