Assessment of treatment of intrahepatic malignancies using chemotherapy via an implantable pump.

摘要: Thirty patients in whom an implantable pump was used for hepatic arterial perfusion of chemotherapeutic agents to treat malignancy were evaluated. Three with primary hepatocellular carcinoma demonstrated less than 50% reduction tumor size. One patient metastatic gastric and one islet cell also showed a decrease the size mass. Among 25 from colon or rectum, 23 had elevated carcinoembryonic antigen (CEA) levels before surgery 75% these revealed at least 50%. Only three 20 followed sequential imaging studies No increase duration survival could be defined when treated compared 13 who not received chemotherapy. The functioned well all patients, but 77% signs toxicity. This experience, coupled review literature, suggests that procedure should regarded as experimental applied liberally until definite benefit can demonstrated.