Cardiovascular, Sympathetic, and Renin-Angiotensin System Responses to Hemorrhage in Vasopressin-Deficient Rats
作者： ROBERT L. ZERBE , GIORA FEUERSTEIN , DIETER K. MEYER , IRWIN J. KOPIN
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摘要: To determine if the subnormal blood pressure recovery after hemorrhage in Brattleboro rats is due to secondary abnormalities renin-angiotensin or sympathetic nervous systems, we measured hemodynamic, catecholamine, and renin activity responses moderate acute anesthetized rats. Results were compared groups of animals matched for either age weight. Blood was significantly blunted (P < 0.01) that control group, but heart rate similar. Basal plasma norepinephrine higher than controls 0.001), response not different. Both epinephrine levels before increased more vasopressin-deficient animals. Plasma vasopressin approximately 10-fold, reaching 790 ± 140 pg/ml age-matched contr...
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