A History and Review of the Renin-Angiotensin System

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DOI: 10.1098/RSPB.1969.0057

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摘要: An outline of the development knowledge renin-angiotensin system is given, and nature enzyme renin, its site within kidney as well in other organs, action on plasma substrate to form first decapeptide which converted biologically active octapeptide, are considered. The methods measurement renin angiotensin body fluids discussed factors causing increased or decreased secretion into blood stream related physiological pathological situations. role a pressor agent, vasoconstrictor stimulator aldosterone production assessed light current knowledge.

参考文章(2)
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Sen S, Bumpus Fm, Smeby Rr, A naturally occurring renin inhibitor. Circulation Research. ,vol. 21, ,(1967)