Significance of Oncogenes in Breast Cancer: Review
作者： J. Fiore , M. V. Viola
DOI: 10.1007/978-3-642-73718-3_4
关键词:
摘要: Proto-oncogenes are a restricted set of cellular genes that frequent targets for mutational alterations in human cancer. Many these were originally identified because they had nucleotide sequence similarity with transforming found acutely retroviruses. The viral oncogene (v-onc) was derived from its homolog (c-one) by genetic recombination and the process insertion into genome acquired structural alterations. detailed comparison structure as compared proto-oncogene has provided critical information on nature mutations obligatory changing normal protein one ability.
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