Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: Synergistic action of oncogenes in vivo

作者: Eric Sinn , William Muller , Paul Pattengale , Isidore Tepler , Racheal Wallace

DOI: 10.1016/0092-8674(87)90449-1

关键词:

摘要: … mated separate strains of transgenie mice that carry either the v-Ha-ras or the c-myc gene … When the MMTVlv-Ha-ras and MMTWc-myc strains ate crossed to yield hybrid mice, their joint …

参考文章(41)
C. R. Taylor, P. K. Pattengale, Experimental models of lymphoproliferative disease. The mouse as a model for human non-Hodgkin's lymphomas and related leukemias. American Journal of Pathology. ,vol. 113, pp. 237- 265 ,(1983)
Ronald W. Davis, Marjorie Thomas, John Cameron, Thomas P. St. John, Stewart Scherer, Richard A. Padgett, [49] Rapid DNA isolations for enzymatic and hybridization analysis Nucleic Acids Part I. ,vol. 65, pp. 404- 411 ,(1980) , 10.1016/S0076-6879(80)65051-4
D Gallahan, C Kozak, R Callahan, A new common integration region (int-3) for mouse mammary tumor virus on mouse chromosome 17. Journal of Virology. ,vol. 61, pp. 218- 220 ,(1987) , 10.1128/JVI.61.1.218-220.1987
W M Lee, M Schwab, D Westaway, H E Varmus, Augmented expression of normal c-myc is sufficient for cotransformation of rat embryo cells with a mutant ras gene. Molecular and Cellular Biology. ,vol. 5, pp. 3345- 3356 ,(1985) , 10.1128/MCB.5.12.3345
P Early, J Rogers, M Davis, K Calame, M Bond, R Wall, L Hood, Two mRNAs can be produced from a single immunoglobulin μ gene by alternative RNA processing pathways Cell. ,vol. 20, pp. 313- 319 ,(1980) , 10.1016/0092-8674(80)90617-0
J. M. Adams, A. W. Harris, C. A. Pinkert, L. M. Corcoran, W. S. Alexander, S. Cory, R. D. Palmiter, R. L. Brinster, The c- myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice Nature. ,vol. 318, pp. 533- 538 ,(1985) , 10.1038/318533A0
Carol J. Quaife, Carl A. Pinkert, David M. Ornitz, Richard D. Palmiter, Ralph L. Brinster, Pancreatic neoplasia induced by ras expression in acinar cells of transgenic mice Cell. ,vol. 48, pp. 1023- 1034 ,(1987) , 10.1016/0092-8674(87)90710-0
Thomas Graf, Fritz v Weizsaecker, Sigrid Grieser, Jean Coll, Dominique Stehelin, Tilo Patschinsky, Klaus Bister, Catherine Bechade, Georges Calothy, Achim Leutz, v-mil induces autocrine growth and enhanced tumorigenicity in v-myc-transformed avian macrophages Cell. ,vol. 45, pp. 357- 364 ,(1986) , 10.1016/0092-8674(86)90321-1