Is There a Role for Liver Transplantation in Non-Colorectal Liver Metastases?

摘要: Due to the high blood flow, especially from intestinal tract via portal vein, liver is a preferred organ for metastases. In case of advanced, irresectable metastases transplantation (LTX) remains an attractive option. However, due recurrence rates or lack data, up date, neuroendocrine tumors (NETs) are only accepted indication LTX in non-colorectal this regard, justified patients which complete tumor resection (R0 resection) NET achievable. A literature review revealed no clear patient selection criteria but should definitively achieve R0 with freedom tumor. The available data regarding outcome following NETs show comparable short- and long-term transplanted other malignancies, e.g. hepatocellular carcinoma, also benign indications MELD (model end-stage disease) era. Thus, most prove better post-transplant lower rate good differentiation tumor, low proliferation index (Ki67), drainage NET.