Relaxin increases sympathetic nerve activity and activates spinally projecting neurons in the paraventricular nucleus of nonpregnant, but not pregnant, rats.

作者: K. Max Coldren , Randall Brown , Eileen M. Hasser , Cheryl M. Heesch

DOI: 10.1152/AJPREGU.00186.2015

关键词:

摘要: Pregnancy is characterized by increased blood volume and baseline sympathetic nerve activity (SNA), vasodilation, tachycardia. Relaxin (RLX), an ovarian hormone elevated in pregnancy, activates...

参考文章(67)
Kaushik P. Patel, Role of paraventricular nucleus in mediating sympathetic outflow in heart failure. Heart Failure Reviews. ,vol. 5, pp. 73- 86 ,(2000) , 10.1023/A:1009850224802
Roger A. L. Dampney, Jaimie W. Polson, Patrick D. Potts, Yoshitaka Hirooka, Jouji Horiuchi, Functional organization of brain pathways subserving the baroreceptor reflex: Studies in conscious animals using immediate early gene expression Cellular and Molecular Neurobiology. ,vol. 23, pp. 597- 616 ,(2003) , 10.1023/A:1025080314925
Anita Matas, Natalija Filipovic, Ljubo Znaor, Snjezana Mardesic, Mirna Saraga-Babic, Katarina Vukojevic, Interplay of proliferation and differentiation factors is revealed in the early human eye development Graefes Archive for Clinical and Experimental Ophthalmology. ,vol. 253, pp. 2187- 2201 ,(2015) , 10.1007/S00417-015-3128-6
Andrew L. Gundlach, Sherie Ma, Qian Sang, Pei-Juan Shen, Loretta Piccenna, Katayoun Sedaghat, Craig M. Smith, Ross A. D. Bathgate, Andrew J. Lawrence, Geoffrey W. Tregear, John D. Wade, David I. Finkelstein, Pascal Bonaventure, Changlu Liu, Timothy W. Lovenberg, Steve W. Sutton, Relaxin family peptides and receptors in mammalian brain. Annals of the New York Academy of Sciences. ,vol. 1160, pp. 226- 235 ,(2009) , 10.1111/J.1749-6632.2009.03956.X
N. Sunn, M. J. McKinley, B. J. Oldfield, Identification of efferent neural pathways from the lamina terminalis activated by blood-borne relaxin. Journal of Neuroendocrinology. ,vol. 13, pp. 432- 437 ,(2001) , 10.1046/J.1365-2826.2001.00650.X
David J. Hornsby, Brian C. Wilson, Alastair J.S. Summerlee, Relaxin and drinking in pregnant rats. Progress in Brain Research. ,vol. 133, pp. 229- 240 ,(2001) , 10.1016/S0079-6123(01)33017-0
A. M. Schreihofer, A. F. Sved, Use of sinoaortic denervation to study the role of baroreceptors in cardiovascular regulation. American Journal of Physiology-regulatory Integrative and Comparative Physiology. ,vol. 266, ,(1994) , 10.1152/AJPREGU.1994.266.5.R1705
L. J. PARRY, A. J. S. SUMMERLEE, Central angiotensin partially mediates the pressor action of relaxin in anesthetized rats. Endocrinology. ,vol. 129, pp. 47- 52 ,(1991) , 10.1210/ENDO-129-1-47
G. E. Callander, R. A. D. Bathgate, Relaxin family peptide systems and the central nervous system Cellular and Molecular Life Sciences. ,vol. 67, pp. 2327- 2341 ,(2010) , 10.1007/S00018-010-0304-Z
Xiao-Jun Du, Tim D. Hewitson, My-Nhan Nguyen, Chrishan S. Samuel, Therapeutic Effects of Serelaxin in Acute Heart Failure Circulation. ,vol. 78, pp. 542- 552 ,(2014) , 10.1253/CIRCJ.CJ-14-0014