Short read fragment assembly of bacterial genomes

摘要: In the last year, high-throughput sequencing technologies have progressed from proof-of-concept to production quality. While these methods produce high-quality reads, they yet reads comparable in length Sanger-based sequencing. Current fragment assembly algorithms been implemented and optimized for mate-paired thus do not perform well on short produced by read technologies. We present a new Eulerian assembler that generates nearly optimal assemblies of bacterial genomes describe an approach assemble case popular hybrid protocol when long are combined.