Human genes differentially expressed in colon cancer

作者: Wilson O Endege , Kathleen E Steinmann , Theodore J Catino , Jon H Astle , Christopher C Burgess

DOI:

关键词:

摘要: This invention relates to novel human genes, proteins expressed by the and variants of proteins. The also diagnostic assays therapeutic agents related genes proteins, including probes, antisense constructs, antibodies. subject nucleic acids have been found be differentially regulated in tumor cells, particularly colon cancer cell lines and/or tissue.

参考文章(12)
J. Trapman, Y. Nozawa, M. P. G. Diesveld, F. T. Bosman, W. N. M. Dinjens, R. Vlietstra, N. Van Belzen, A. C. J. Van Der Made, N. A. Groen, A novel gene which is up-regulated during colon epithelial cell differentiation and down-regulated in colorectal neoplasms Laboratory Investigation. ,vol. 77, pp. 85- 92 ,(1997)
Elissa N. Rivers, Glenn D. Steele, Lan Bo Chen, Hsiukang Yow, T. S. Ravikumar, Jau Min Wong, Ken-ichi Mafune, Ubiquitin-Ribosomal Protein S27a Gene Overexpressed in Human Colorectal Carcinoma Is an Early Growth Response Gene Cancer Research. ,vol. 53, pp. 1916- 1920 ,(1993)
Edward R. Lavallie, Vikki Spaulding, Lisa A. Racie, John M. Mccoy, Michael J. Agostino, Maurice Treacy, David Merberg, Kenneth Jacobs, Secreted expressed sequence tags (sests) ,(1998)
Ben Zion Vider, Amazia Zimber, Dania Hirsch, Dov Estlein, Eric Chastre, Sophie Prevot, Christian Gespach, Abraham Yaniv, Arnona Gazit, Human colorectal carcinogenesis is associated with deregulation of homeobox gene expression. Biochemical and Biophysical Research Communications. ,vol. 232, pp. 742- 748 ,(1997) , 10.1006/BBRC.1997.6364
Soojin Ryu, Sharleen Zhou, Andreas G. Ladurner, Robert Tjian, The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1. Nature. ,vol. 397, pp. 446- 450 ,(1999) , 10.1038/17141
Wei Gu, Sohail Malik, Mitsuhiro Ito, Chao-Xing Yuan, Joseph D Fondell, Xiaolong Zhang, Ernest Martinez, Jun Qin, Robert G Roeder, A Novel Human SRB/MED-Containing Cofactor Complex, SMCC, Involved in Transcription Regulation Molecular Cell. ,vol. 3, pp. 97- 108 ,(1999) , 10.1016/S1097-2765(00)80178-1
Clifford W. Schweinfest, Kelly W. Henderson, Jian-Ren Gu, Stavros D. Kottaridis, Stavros Besbeas, Evi Panotopoulou, Takis S. Papas, Subtraction hybridization cDNA libraries from colon carcinoma and hepatic cancer Gene Analysis Techniques. ,vol. 7, pp. 64- 70 ,(1990) , 10.1016/0735-0651(90)90042-E
Carles Serra-Pagès, Quintus G. Medley, May Tang, Anne Hart, Michel Streuli, Liprins, a Family of LAR Transmembrane Protein-tyrosine Phosphatase-interacting Proteins Journal of Biological Chemistry. ,vol. 273, pp. 15611- 15620 ,(1998) , 10.1074/JBC.273.25.15611