Voltage gating of Ca2+-activated potassium channels in human lymphocytes
作者： László Mátyus , Carlo Pieri , Rina Recchioni , Fausto Moroni , László Bene
DOI: 10.1016/0006-291X(90)91396-A
关键词:
摘要: The effect of membrane potential on Ca2+ activated K+ channels was studied human peripheral lymphocytes. Membrane monitored using bisoxonol and flow cytometry. 1 mM in the presence 2 microM ionomycin depolarized control cell population, while 100 caused hyperpolarization. However had a hyperpolarizing previously partially cells. Potassium channel blockers did not influence depolarization, they inhibited Based experimental evidence voltage gating is suggested.
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