Psychotropic prescription practices in east Asia: looking back and peering ahead.

摘要: Purpose of review The present focuses on the pharmacoepidemiological issues psychotropic drug use in countries within east Asia, with special emphasis antipsychotic, antidepressant and benzodiazepine prescriptions. Pharmacogenetic studies different ethnic groups are also reviewed. Recent findings have revealed prevalence antipsychotic polytherapy (defined as more than one antipsychotic; up to 45.7%), less conservative 1000 mg/day chlorpromazine equivalents; 17.9%) depot (up 15.3%) populations Asia. Clozapine is commonly prescribed 60%) China. There a trend increasing second-generation Asian countries. Up 67.5% patients received newer antidepressants such selective serotonin reuptake inhibitors. Benzodiazepine medications used 29.9% study populations. Socioeconomic factors appear be major common that affect prescription antipsychotics antidepressants. associated response, weight gain extrapyramidal side effects been examined. Treatment adherence pharmacoeconomic relatively understudied. Summary Future prescribing trends need focus children, adolescent elderly patient populations, impact changing long-term their caregivers, well pharmacogenetic factors, which can potentially pave way for better individualized drugs