Radiopharmaceutiques et métastases osseuses : quelles molécules pour quels patients et dans quelles indications ?

作者: J. Dubreuil , C. Houzard , K. Saddoune , F. Giammarile

DOI: 10.1007/S10269-015-2498-Z

关键词:

摘要: Le principe des explorations scintigraphiques est de determiner, et le plus souvent representer sous forme d’images, la biodistribution d’un radiopharmaceutique au sein l’organisme. L’imagerie hybride, anatomique fonctionnelle, augmente sensibilite specificite examens scintigraphiques, ce notamment dans les cas difficiles ou l’analyse separee deux ne permet trancher avec certitude quant a nature signification anomalies. La scintigraphie osseuse aux diphosphonates techneties l’examen radio-isotopique classique l’etude pathologie osseuse. Dans certains neanmoins, tomographie par emission positons (TEP) FDG sensible detection metastases osteolytiques. radiotherapie metabolique consiste en l’administration radioelement source non scellee, dont rayonnements vont detruire cellules qui ont accumule selectivement produit. prise charge douleur constitue un probleme majeur, cancer mammaire prostatique presence peut demeurer compatible une survie longue duree. cadre, diminuer douleurs secondaires osseuses, association medicaments antalgiques.

参考文章(38)
Harry K. Genant, Paul B. Hoffer, Allan H. Rappaport, Unifocal bone findings by scintigraphy. Clinical significance in patients with known primary cancer. Western Journal of Medicine. ,vol. 129, pp. 188- 192 ,(1978)
Manuel L. Brown, Significance of the solitary lesion in pediatric bone scanning: concise communication. The Journal of Nuclear Medicine. ,vol. 24, pp. 114- 115 ,(1983)
Ignac Fogelman, Daniel I. Boxer, Colin E. C. Todd, Robert Coleman, Bone secondaries in breast cancer: the solitary metastasis. The Journal of Nuclear Medicine. ,vol. 30, pp. 1318- 1320 ,(1989)
Francis, A.J. Tofe, W.J. Harvey, Correlation of neoplasms with incidence and localization of skeletal metastases: An analysis of 1,355 diphosphonate bone scans. The Journal of Nuclear Medicine. ,vol. 16, pp. 986- 989 ,(1975)
J L Alexander, P J Gillespie, G A Edelstyn, Changes in 87mSr concentractions in skeletal metastases in patients responding to cyclical combination chemotherapy for advanced breast cancer. The Journal of Nuclear Medicine. ,vol. 16, pp. 191- 193 ,(1975)
Abass Alavi, Edward Gosfield, Bruce Kneeland, Comparison of radionuclide bone scans and magnetic resonance imaging in detecting spinal metastases. The Journal of Nuclear Medicine. ,vol. 34, pp. 2191- 2198 ,(1993)
Thomas Wiebe, Helena Willen, Kristian Herrlin, Flare phenomenon in osteosarcoma after complete remission The Journal of Nuclear Medicine. ,vol. 36, pp. 1429- 1431 ,(1995)
Rahul C. Mehta, Michael A. Wilson, Scott B. Perlman, False-negative bone scan in extensive metastatic disease: CT and MR findings. Journal of Computer Assisted Tomography. ,vol. 13, pp. 717- 719 ,(1989) , 10.1097/00004728-198907000-00037
J A Frank, A Ling, N J Patronas, J A Carrasquillo, K Horvath, A M Hickey, A J Dwyer, Detection of malignant bone tumors: MR imaging vs scintigraphy. American Journal of Roentgenology. ,vol. 155, pp. 1043- 1048 ,(1990) , 10.2214/AJR.155.5.2120933
Ignac Fogelman, Skeletal uptake of diphosphonate: A review European Journal of Nuclear Medicine and Molecular Imaging. ,vol. 5, pp. 473- 476 ,(1980) , 10.1007/BF00252034