Psychological outcomes in long-term survivors of childhood leukemia, Hodgkin's disease, and non-Hodgkin's lymphoma: a report from the Childhood Cancer Survivor Study.

摘要: Objective. To evaluate and compare psychological outcomes in long-term survivors of pediatric leukemia, Hodgkin’s disease, non-Hodgkin’s lymphoma sibling controls. Methods. Adult childhood (N = 5736) controls 2565) were administered a follow-up questionnaire allowing assessment symptoms associated with depression somatic distress. Results. The majority respondents this study did not demonstrate symptomatology indicative or Survivors, however, significantly more likely than to report Women indicate distress men; difference vary by survivor/sibling status. Similarly, socioeconomic (SES) variables predicted symptomatic levels for both siblings, these effects Among survivors, addition gender SES, the only treatment variable that scores indicating depressive was exposure intensive chemotherapy. Exposure chemotherapy also symptoms. No other medical variables, including diagnostic category, age at diagnosis, time since duration treatment, Conclusions. This large, sibling-controlled, multisite young adult found had significant increased risk reporting added risk. However, being cancer survivor compound SES on 2 measured. ability gender, treatment-related predict cohort calls future research into varied biological psychosocial pathways which influences functioning.