作者: L.J. Murdin
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摘要: Migraine can be conceptualised as a disorder of sensory processing, manifest by such symptoms headache (pain), phonophobia and photophobia. Current models of migraine pathophysiology incorporate significant role for the brainstem. Vestibular migraine (VM) is subtype in which brainstem dysfunction has been documented. The condition known to have effect on mental health. This study was designed investigate disturbances audiovestibular brainstem function vestibular migraine four part study: 1. Otoacoustic emission suppression contralateral noise, test auditory efferent pathway function, measured group 33 VM patients compared with 31 healthy controls. Regression analysis showed higher rate abnormality amongst the (p=0.03). 2. Vestibular evoked myogenic potentials were recorded 30 patients and 35 healthy Recordings abnormal responses than amongst controls (p=0.008). 3. potential stimuli act triggers investigated by observing testing or control 148 individuals. Vestibular stimulation associated increase probability of developing attack over following 24 hour period (p=0.01). 4. Psychological symptoms depression anxiety assessed using questionnaires 39 44 patients dizziness other causes. Although had significantly higher load anxiety, regression modelling showed that this largely accounted an excess symptoms. In conclusion, documents number audiovestibular processing abnormalities using variety techniques. has significant effect psychological wellbeing, via balance symptoms.