Optimizing Nutrition for the Patient after Pancreaticoduodenectomy: Pancreatic Insufficiency

作者: Jeannine B. Mills

DOI: 10.1007/978-3-319-53091-8_12

关键词:

摘要: Pancreatic cancer can have a deleterious effect on patient’s nutritional status. There is high prevalence of cachexia as well malnutrition in many patients with pancreatic cancer. Exocrine insufficiency (EPI) contribute to secondary steatorrhea-related symptoms and malabsorption both lending limitations food intake, absorption, subsequently weight loss. EPI diagnosed one out two preoperatively though this markedly increases postoperatively. It unfortunately not assessed routinely or even at the time diagnosis, when treated, enzyme replacement therapy too often suboptimal. As new oncologic protocols present for cancer, it imperative that status optimized enabling endure surgery, (neo)adjuvant therapies, palliative options an effort improve outcomes quality life. Future studies are direly needed better understand course over optimal treatment

参考文章(13)
Michael J. Bartel, Horatio Asbun, John Stauffer, Massimo Raimondo, Pancreatic exocrine insufficiency in pancreatic cancer: A review of the literature Digestive and Liver Disease. ,vol. 47, pp. 1013- 1020 ,(2015) , 10.1016/J.DLD.2015.06.015
Marco Cavallini, Genoveffa Balducci, Giovanni Ramacciato, Marco La Torre, Vincenzo Ziparo, Giuseppe Nigri, Malnutrition and pancreatic surgery: Prevalence and outcomes Journal of Surgical Oncology. ,vol. 107, pp. 702- 708 ,(2013) , 10.1002/JSO.23304
E. C. M. Sikkens, D. L. Cahen, J. de Wit, C. W. N. Looman, C. van Eijck, M. J. Bruno, Prospective assessment of the influence of pancreatic cancer resection on exocrine pancreatic function British Journal of Surgery. ,vol. 101, pp. 109- 113 ,(2013) , 10.1002/BJS.9342
Tara C Mueller, Jeannine Bachmann, Marc E Martignoni, Marc A Burmeister, Cachexia and pancreatic cancer: Are there treatment options? World Journal of Gastroenterology. ,vol. 20, pp. 9361- 9373 ,(2014) , 10.3748/WJG.V20.I28.9361
Stavros Sougioultzis, Elias Skopelitis, Nikitas Papadoniou, Efstathios Papalambros, Christos Kosmas, Michalis Tzivras, Gavrilos Karatzas, Nikolas Tsavaris, Aris Polyzos, George Papastratis, Despina Mouratidou, Kostadinos Gennatas, Prognostic Factors in Patients with Locally Advanced (Unresectable) or Metastatic Pancreatic Adenocarcinoma: A Retrospective Analysis Anticancer Research. ,vol. 28, pp. 543- 549 ,(2008)
J MATSUMOTO, L TRAVERSO, Exocrine function following the whipple operation as assessed by stool elastase Journal of Gastrointestinal Surgery. ,vol. 10, pp. 1225- 1229 ,(2006) , 10.1016/J.GASSUR.2006.08.001
Wendy Davidson, Susan Ash, Sandra Capra, Judith Bauer, Cancer Cachexia Study Group, None, Weight stabilisation is associated with improved survival duration and quality of life in unresectable pancreatic cancer. Clinical Nutrition. ,vol. 23, pp. 239- 247 ,(2004) , 10.1016/J.CLNU.2003.07.001
Pankaj Vashi, Brenten Popiel, Carolyn Lammersfeld, Digant Gupta, Outcomes of systematic nutritional assessment and medical nutrition therapy in pancreatic cancer. Pancreas. ,vol. 44, pp. 750- 755 ,(2015) , 10.1097/MPA.0000000000000336
M. Kanda, T. Fujii, Y. Kodera, S. Nagai, S. Takeda, A. Nakao, Nutritional predictors of postoperative outcome in pancreatic cancer British Journal of Surgery. ,vol. 98, pp. 268- 274 ,(2010) , 10.1002/BJS.7305