Methotrexate and misoprostol for early abortion: a multicenter trial. Acceptability

摘要: A prospective trial was conducted including 300 pregnant women seeking elective abortion to evaluate the efficacy and acceptability of methotrexate misoprostol for at < or = 56 days gestation. Subjects received 50 mg/m2 intramuscularly followed 7 later by 800 micrograms vaginally. The dose repeated next day if did not occur. Efficacy is reported elsewhere. were questioned before study as their reasons choosing a medical past experience with surgical abortion. After completed, about experience. All questions asked in an open-ended manner. Main outcome measures included participation, attitudes nonsurgical experience, feelings preference most common reason cited why chose have avoid some aspect surgery (48.4%). percent who that avoiding important choice varied site according whether woman had prior Upon completion study, 73.4% stated it good 19.5% neutral 7.1% bad 1.0% gave no response. When what method they would choose another abortion, 83.5% this rather than Intramuscular vaginal are acceptable desirable