Novel tandem triplication of 1q in a patient with a myelodysplastic syndrome
作者： Peter R. Papenhausen , Ellen Wolkin-Friedman , Catherine Pekzar-Wissner
DOI: 10.1016/0165-4608(84)90126-2
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摘要: This is a report of patient with myelodysplastic syndrome characterized by symptomatic neutropenia whose bone marrow aspirates have consistently demonstrated an unusual cytogenetic anomaly. The abnormality present in all metaphases consisted tandem triplication portion the long arm chromosome #1, resulting tetrasomy section this ( 1q21 -32). Duplications #1 were observed as nonrandom event various malignant states. In addition, these precise breakpoints can be increasingly correlated duplications.
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