Enantioselectivitiy of the nitrile hydratase from Rhodococcus equi A4 towards substituted ( R,S )-2-arylpropionitriles
作者： Ludmila Mart�nkov� , Andreas Stolz , Hans-Joachim Knackmuss
DOI: 10.1007/BF00129734
关键词:
摘要: Rhodococcus equi A4 cells containing a nitrile hydratase and an amidase converted (R,S)-2-(4-methoxyphenyl)-propionitrile into the corresponding (S)-acid (e.e. 87%) (R)-nitrile > 95%) in 49% yield. The same reaction using (R,S)-2-(4-chlorophenyl)-propionitrile gave 52%) 20 34% yield, respectively.
springer.com
sci-hub.se 参考文章(11)
Norman Layh, Hans-Joachim Knackmuss, Andreas Stolz, Enantioselective hydrolysis of ketoprofen amide by Rhodococcus sp. C3II and Rhodococcus erythropolis MP 50 Biotechnology Letters. ,vol. 17, pp. 187- 192 ,(1995) , 10.1007/BF00127986
Thomas Gilligan, Hideaki Yamada, Toru Nagasawa, Production of S-(+)-2-phenylpropionic acid from (R,S)-2-phenylpropionitrile by the combination of nitrile hydratase and stereoselective amidase in Rhodococcus equi TG328. Applied Microbiology and Biotechnology. ,vol. 39, pp. 720- 725 ,(1993) , 10.1007/BF00164456
Ludmila Martínková, Petr Olšovský, Irena Přepechalová, Vladimír Křen, Biotransformations of aromatic diniitriles using Rhodococcus equi cells Biotechnology Letters. ,vol. 17, pp. 1219- 1222 ,(1995) , 10.1007/BF00128389
Toshi Irie, Akio Fukuzawa, Motowo Izawa, Etsuro Kurosawa, Laurenisol, a new sesquiterpenoid containing bromine from yamada Tetrahedron Letters. ,vol. 10, pp. 1343- 1346 ,(1969) , 10.1016/S0040-4039(01)87881-3
Timothy Beard, Mark A. Cohen, Julian S. Parratt, Nicholas J. Turner, John Crosby, Jock Moilliet, Stereoselective hydrolysis of nitriles and amides under mild conditions using a whole cell catalyst Tetrahedron-asymmetry. ,vol. 4, pp. 1085- 1104 ,(1993) , 10.1016/S0957-4166(00)80215-3
R. Bauer, B. Hirrlinger, N. Layh, A. Stolz, H.-J. Knackmuss, Enantioselective hydrolysis of racemic 2-phenylpropionitrile and other (R,S)-2-arylpropionitriles by a new bacterial isolate, Agrobacterium tumefaciens strain d3 Applied Microbiology and Biotechnology. ,vol. 42, pp. 1- 7 ,(1994) , 10.1007/BF00170215
Shun-ichi Masutomo, Ayumu Inoue, Kazuo Kumagai, Rika Mural, Satoshi Mitsuda, Enantioselective Hydrolysis of (RS)-2-Isopropyl-4′-chlorophenylacetonitrile byPseudomonassp. B21C9 Bioscience, Biotechnology, and Biochemistry. ,vol. 59, pp. 720- 722 ,(1995) , 10.1271/BBB.59.720
Mark A. Cohen, Julian S. Parratt, Nicholas J. Turner, Enantioselective hydrolysis of nitriles and amides using an immobilised whole cell system Tetrahedron: Asymmetry. ,vol. 3, pp. 1543- 1546 ,(1992) , 10.1016/S0957-4166(00)86056-5
Michelle L. Gradley, Christopher J. Knowles, Asymmetric hydrolysis of chiral nitriles by Rhodococcus rhodochrous NCIMB 11216 nitrilase Biotechnology Letters. ,vol. 16, pp. 41- 46 ,(1994) , 10.1007/BF01022621
Norman Layh, Andreas Stolz, Joachim Böhme, Franz Effenberger, Hans-Joachim Knackmuss, Enantioselective hydrolysis of racemic naproxen nitrile and naproxen amide to S-naproxen by new bacterial isolates. Journal of Biotechnology. ,vol. 33, pp. 175- 182 ,(1994) , 10.1016/0168-1656(94)90109-0