Enantioselective hydrolysis of nitriles and amides using an immobilised whole cell system
作者： Mark A. Cohen , Julian S. Parratt , Nicholas J. Turner
DOI: 10.1016/S0957-4166(00)86056-5
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摘要: Abstract An immobilised whole cell catalyst SP361 has been shown to hydrolyse a range of 2-alkyl arylacetonitriles 1a–3a and amides 2b, 3b with good excellent enantioselectivity. The absolute configuration the derived and/or carboxylic acids shows remarkable changes according structure nitrite substrate.
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